Traditional cross-linking method

Extensive modification of HA

• * Side effects due to high chemical crosslinking
  * Decreased duration due to short chain bonding
• 

CCT cross-linking method

Minimal modification of HA to stabilize the natural network

• * Minimize side effects due to minimal chemical crosslinking
  * Increase durability by maintaining the long chain of hyaluronic acid
• 

CCT cross-linking method

• Biphasic filler – Elasticity and phase angle

  

• Monophasic filler – Elasticity and total BDDE

  

• Spherical filler – Long lasting hyaluronic acid filler

  The world’s first commercialized Beaded long lasting filler with more safety and volumizing

  

  Optimized design for human body injection

  Macrophage activity affects physical chemistry such as particle size and chemical structure

  Normal HA filler * Larger area * Irregular shape → more stimulation to macrophage → more cytokine eruption → more inflammation	VS	Beaded HA filler * Smaller area * Soft and regular shape

• Thermal Sensitive Spherical filler – Thermal Sensitive Elasticity

  The world’s first commercialized temperature sensitivity Beaded long lasting filler

  

  while showing an appropriate elasticity value at room temperature, after injection of temperature sensitivity filler, gradually increase elasticity and duration

  

Diversification of hyaluronic acid fillers

• Hyaluronic acid filler

  - Applying a new cross-linking method

  - Implementing minimization of side effects

  - Minimizing HA and cross-linking agent

  - Volumizing effects on the face

• Temperature-sensitive filler

  - Higher safety compared to the existing fillers

  - Confirming the safety through clinical tests

  - Entering new markets with products whose safety efficacy has been secured by clinical tests

• Mezzo filler

  - Applying high-purity raw materials derived from natural ingredients

  - Confirming the safety through clinical tests

  - Facilitating the time for wound healing

  - Confirming collagen production